Getting Started

Step 1. Click the “Ontologies” subsection under your “Data Catalog” menu, located on the left-hand side of your Layar home page.

Step 2. Click the ontology name to see the Ontology View for that ontology, with the terms, synonyms, and related metadata.

Step 3. Search andclick on a term to see its references, synonyms, and other metadata. Here I have searched for “Antineoplastic chemotherapy regimen“.

Now you are ready to modify this ontology term.

Add a Parent Node

1. On the “+” Icon, to the right of the Ontology Search Bar.
2. Complete the information on the modal pop up for the new parent node, including the term, synonyms, and any database that references this entity with its own unique ID.
3. Click “Save“
4. You will now see the parent node within the ontology, with an Ontology Card with the information you provided in step 2.

Add a Child Node

1. On the Ontology Card, click the icon with three vertical dots and select “Add Child Node“.2. Complete the information on the modal pop up for the child node, including the term, synonyms, and any database that references this entity with its own unique ID. 3. Click “Save” 4. You will now see the child node underneath the parent term, with an Ontology Card with the information you provided in step 2. Edit an Ontology TermTo Edit, click the icon with three vertical dots on the Ontology Card and select “Edit“.For any of the properties of that term, you can add additional values (one per line). For example, I added in three new references for my “Xrefs” property below. Click Save. The new values will be populated in the property they were added to. Delete an Ontology TermTo Delete, click the icon with three vertical dots on the Ontology Card and select “Delete”. Confirm you want to permanently remove this ontology term. Any child nodes underneath that ontology term will also be permanently deleted.

While Layar can handle keyword and boolean search, we find it helpful to provide an overview of boolean operators to enhance your Layar search experience. 

What are Boolean Operators? 

If you have ever Googled something, you have already created Boolean search strings. If you use it without realizing it, you can learn a few Boolean operators that will drastically improve your current sourcing efforts.

NOTE: Be sure to include single or double quotes to trigger the Boolean search.

Boolean Operators

1. AND
   Narrows your search results to include only relevant results that contain your required keywords (e.g. “Alzheimer’s” AND “target” will only yield documents that have both of those keywords).
   
2. OR
   Expands your search results so all results must contain at least one, if not more, of your defined keywords or phrases. OR is useful for two scenarios: (1) you need to include all synonyms for a given title, phrase or word (e.g. interleukin-1 OR IL-1 OR IL1), or (2) creating a list of all possibilities where you only need at least one of the keywords to be returned (e.g. Merck OR Pfizer OR Novartis).
   
3. NOT
   Limits your search by excluding defined keywords and/or phrases from your results (e.g. drug NOT vitamin reveals all results that discuss drugs, excluding those that also mention “vitamin”).
   
4. “Quotation Marks”
   Use quotes around a phrase that needs to be returned in that exact order. For example, “United States of America” will yield results with that exact term, but without quotes, each word in the phrase will be treated separately, as if you used OR between each word (United OR States OR of OR America).
   
5. (Parenthesis)
   Parentheses are used to give priority to the keywords contained within over the other elements around it. As a rule of thumb, parentheses should be used around OR statements, ensuring the search engine properly resolves the OR statement before moving on to other operators. For example, (Tumor OR Carcinoma OR Cancer) AND treatment will yield results that mention treatment and any one or several of the key terms in parenthesis.
   
6. Asterisks*
   * on a term matches multiple characters preceding a stem. For example, hydroxych* yields results for hydroxychloroquine, hydroxycholesterol, etc.
   
7. Question Mark?
   ? on a term matches a single character preceding a stem. For example, a?duction can yield results for abduction and adduction. Another example can be anemi? to find results for anemia and anemic.